For maximum comfort, make sure to keep the soft, padded center in place when applying. This item works best when applied to clean, dry skin that is free of deodorants, perfumes, lotions, or powders. These can be applied after the product is adhered to the skin. Instructions For Removal: Use a small amount of baby oil and apply around the edges of the petals with a cloth. The baby oil should allow the medical grade adhesive to release from the skin before your Petals can be slowly removed. We recommend that you perform a skin test 24 hours before extended use.